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Cell & Gene Therapies
CAR‑T, CRISPR, in vivo delivery, manufacturing, and long‑term follow‑up.
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Latest in Cell & Gene Therapies
IASO Bio's CD20-Targeted In Vivo CAR-T Therapy IASO208 Receives FDA IND Clearance
7+ hour, 10+ min ago (110+ words) Sep 16, 2026, 05:47 ET — IASO208 is the first China-originated lentiviral vector-based in vivo CAR-T therapy to receive FDA IND clearance — Supported by early clinical data from an investigator-initiated trial in China, IASO208 is expected to advance directly into a Phase 1b clinical study in the…...
News: Clinical-Scale WAS Editing Meets GMP and Safety Benchmarks
9+ hour, 10+ min ago (367+ words) Clinical-Scale WAS Editing Meets GMP and Safety Benchmarks CRISPR Medicine News Clinical-Scale WAS Editing Meets GMP and Safety Benchmarks A UCL-led team has developed a clinical-scale CRISPR-Cas9-AAV6 workflow intended to correct Wiskott-Aldrich syndrome in haematopoietic stem and progenitor cells, reaching…...
She Can’t Feel Pain or Anxiety. Her Genetic Mutations Hold the Key to Eliminating Human Suffering, Scientists Claim.
15+ hour, 13+ min ago (344+ words) A life without pain seems miraculous. But denying this hallmark of human existence could come with its own set of challenges. Cameron was diagnosed with “pain insensitivity disorder,” which covers a spectrum of conditions that spring from a well of…...
Public treats risks for low intelligence and heart disease similarly when selecting embryos
20+ hour, 34+ min ago (428+ words) Preimplantation genetic testing is a medical procedure used during in vitro fertilization. Before an embryo is transferred to a uterus, doctors extract a small number of cells and analyze the genetic material. Polygenic testing is a specific type of this…...
Ride to get up to $7.3M from CF Foundation for gene delivery tech
22+ hour, 12+ min ago (367+ words) Company says its platform could make genetic medicines more feasible in CF Written by Patricia Inácio, PhD | Sept. 15, 2026 The Cystic Fibrosis Foundation is investing up to $7.3 million in Ride Therapeutics to develop nonviral carriers of genetic therapies intended to reach…...
A 3-Year-Old’s Cancer Disappeared After Just Two Doses of Experimental CAR-T Therapy
22+ hour, 20+ min ago (438+ words) Baylor College of Medicine researchers achieved full 12-month remission in a toddler using two outpatient GPC3-targeted CAR T infusions Hepatoblastoma is the most common malignant liver tumor in children and carries a poor prognosis once frontline therapy fails. At diagnosis,…...
Cellectis exits CAR-T development to focus on in vivo gene editing for metabolic diseases
22+ hour, 47+ min ago (549+ words) AllSci Cellectis (Euronext Growth: ALCLS / Nasdaq: CLLS), the Paris-based gene editing company, is ending internal development of its allogeneic CAR-T programs and repositioning around in vivo gene editing for chronic metabolic diseases. The shift follows slower enrollment and rising development…...
Study links faecal IgA levels with dogs’ atopic dermatitis
1+ day, 2+ hour ago (395+ words) Faecal IgA was found to be significantly lower in dogs with canine atopic dermatitis compared with healthy controls. Image: Todorean Gabriel / Adobe Stock Researchers have shed new light on a chronic skin disease in dogs after discovering it is associated…...
CAR T-cell therapy shows sustained benefits in three gMG patients
1+ day, 1+ hour ago (731+ words) Study findings support miv-cel as a promising treatment approach Written by Andrea Lobo | Sept. 15, 2026 The investigational CAR T-cell therapy KYV-101, or mivocabtagene autoleucel (miv-cel), improves muscle strength and daily functioning in people with hard-to-treat generalized myasthenia gravis (gMG), with benefits…...
Circio Holding ASA (CRNA) Secures NOK 200 Million via Private Placement to Boost In Vivo CAR-T Cell Therapy Development
1+ day, 2+ hour ago (19+ words) Private Placement at NOK 200 Million with 9% Discount to Support circVec In Vivo CAR-T Therapy Programme Kalkine Media...